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Dragon's blood the ingredient that regenerates skin
Dragon's blood stands out as one of the most versatile actives in modern formulation. Extracted from the latex of the Croton lechleri tree, it combines cell regeneration, antioxidation and anti-inflammatory effect. Cobiosa offers it in water-soluble and oil-soluble versions, with in vitro tests and epigenetic activity backing its efficacy.
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Dragon's Blood
Dragon's Blood LP
- Dragon's blood in cosmetics: origin and potential
Cobiosa Dragon's Blood: efficacy data
Dragon's Blood applications in formulation
Dragon's Blood in Cosmetics: Origin and Potential
Dragon's blood extract comes from the latex of the Croton lechleri tree, native to the Amazon. Its composition of proanthocyanidins, taspine and lignans gives it a unique multifunctional activity profile, with regenerating, healing and antioxidant properties scientifically documented.
What is Croton lechleri extract
Dragon's blood is the deep red latex that exudes from the Croton lechleri tree when cut. Composed mainly of proanthocyanidins, taspine and lignans, this botanical extract concentrates extraordinary biological activity that sets it apart from other plant actives in current cosmetic formulation.
Exotic actives with solid scientific backing are the new frontier of cosmetic innovation. Dragon's Blood is one of the fastest growing actives in global formulation searches and one of the most cited in publications on skin regeneration and inflammation. It aligns with the nature-powered actives and clinical naturals trends, dominant in premium European and North American brand launches.
Why does Dragon's Blood lead among natural bioactive actives?
Dragon's Blood in Cosmetics: Skin Regenerating Active
Contents
Cobiosa Dragon's Blood: Efficacy Data
Cobiosa's Dragon's Blood version provides in vitro data that justifies its use in high-efficacy formulations. The tests performed show significant results both in cell regeneration and antioxidant capacity, reinforced by epigenetic activity that acts directly on the expression of key skin genes.
Cell regeneration: +86% in dermal fibroblasts
In the in vitro scratch test, Cobiosa Dragon's Blood produced an increase of up to 86% in the proliferation and migration of human dermal fibroblasts at 10 μg/mL after 48 hours. In the DPPH antioxidant assay, it showed an EC50 of 6.85 ± 2.28 μg/mL, activity similar to vitamin C and significantly superior to vitamin E.
Epigenetic activity: action on 10 key genes
Dragon's Blood modulates microRNA expression through a gene on-off mechanism. It stimulates FRK, WNT4 and NRG4 to promote healing; inhibits IL1B, IL6 and PTGS2 to reduce inflammation; activates GPX2 for antioxidant defence; reinforces barrier function through TLR 3, 5 and 6; and activates AQP3 for natural hydration via aquaporin 3.
Dragon's Blood Applications in Formulation
Dragon's Blood comes in two versions that cover virtually any type of formulation. The water-soluble version allows it to be incorporated into serums, gels and masks, while Dragon's Blood LP, its oil-soluble variant, opens the door to anhydrous formulas and high-performance lip products.
Water-soluble version: serums, gels and masks
The water-soluble version of Dragon's Blood is incorporated at 3-5% in calming serums for sensitive skin, repairing gels that accelerate skin recovery and regenerating night masks. Its multifunctional profile allows developing products that combine hydration, calming, pollution protection and active repair in a single application.
Dragon's Blood LP: oil-soluble formulation and lip products
Dragon's Blood LP is the oil-soluble version of the active, formulated with Argania spinosa extract and shea butter. Ideal for lip balms, anhydrous products and formulas where an aqueous vehicle is not viable, it provides the same regenerating and antioxidant properties in a format compatible with complex lipid bases.
Definition
Dragon's blood cosmetics is today one of the raw materials with the greatest scientific backing in regeneration, antioxidation and inflammatory control. Contact Cobiosa's technical team to request reference formulations or download the complete active monograph.